Src antibody (pTyr419)

Catalog No. ABIN3029559

This anti-Src antibody is a Rabbit Polyclonal antibody detecting Src in ELISA and DB. Suitable for Human.

Quick Overview for Src antibody (pTyr419) (ABIN3029559)

Target: Src (Proto-oncogene tyrosine-protein kinase Src (Src))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Src antibody is un-conjugated

Application: ELISA, Dot Blot (DB)

Product Details anti-Src Antibody

Binding Specificity: pTyr419

Cross-Reactivity (Details): Expected species reactivity: Bovine, Chicken, Mouse, Pig, Rat, Xenopus, Zebrafish

Purification: Antigen affinity purified

Immunogen: This phospho-Src antibody was produced from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding pY419 of human Src.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the phospho-Src antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Dot blot: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the phospho-Src antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for Src

Target: Src (Proto-oncogene tyrosine-protein kinase Src (Src))

Alternative Name: Src

Background: This proto-oncogene may play a role in the regulation of embryonic development and cell growth. This protein is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-Src kinase.

UniProt: P12931

Pathways: JAK-STAT Signaling, Neurotrophin Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Cellular Response to Molecule of Bacterial Origin, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling, Platelet-derived growth Factor Receptor Signaling, Thromboxane A2 Receptor Signaling, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling